Dosage Charts › Argireline
Skin & Repair
Argireline Guide & Dosage Chart
A topical peptide studied for expression-line softening.
Also known asAcetyl Hexapeptide-8
Routesubcutaneous
Argireline — Dosage chart
Every row cited| Goal | Dose | Frequency | Duration | Evidence | Source |
|---|---|---|---|---|---|
| Anti-wrinkle / wrinkle depth reduction (topical cosmetic use) | 10 mg | 2x/day | 4 weeks | Clinical | PMID 29371611 PMID 23417317 |
| Anti-wrinkle / wrinkle depth reduction (O/W emulsion, 10% concentration) | 10 mg | per trial | 30 days | Clinical | PMID 18498523 |
| Safe cosmetic use concentration limit | 0.005 mg | per trial | per trial | Consensus | PMID 40673537 |
For research and educational use only. Not medical advice.
Argireline FAQ
What is the typical Argireline dosage?
In research, Argireline has been studied at 10 mg 2x/day for Anti-wrinkle / wrinkle depth reduction (topical cosmetic use) (4 weeks). See the chart above for every studied protocol, each cited.
How do you reconstitute Argireline?
Mix the lyophilized Argireline with bacteriostatic water, then use the concentration to find your draw volume. The calculator on this page does the math for you.
Is Argireline dosing backed by research?
Yes — every dose on this chart maps to a peer-reviewed source. Figures we cannot anchor to a study are left out. Argireline is a research compound for laboratory use only.
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